田平

研究概况

论文成果

• [1]liqinghua,zhangguishan.Nature-inspired catalytic asymmetric rearrangement of cyclopropylcarbinyl cation, SCIENCE ADVANCES, 2023, ,9(19)
• [2]wangyajie.A Highly Enantioselective Homoenolate Michael Addition/ Esterification Sequence of Cyclohexadienone-Tethered Enals via NHC Catalysis, ORGANIC LETTERS, 2023,
• [3]zhaojiaying,liaoqi,王峥涛.Thiourea-Promoted Cascade Dihalogenation-Cyclization of Cyclohexadienone-Containing 1,6-Enynes, ADVANCED SYNTHESIS & CATALYSIS, 2023, ,365(4):482-489
• [4]gaodingding,tangshuai,cenyixin.Discovery of Novel Drug-like PHGDH Inhibitors to Disrupt Serine Biosynthesis for Cancer Therapy, JOURNAL OF MEDICINAL CHEMISTRY, 2023, ,66(1):285-305
• [5]zhangfumao,huangting,wangfeng.Discovery of highly potent covalent SARS-CoV-2 3CLpro inhibitors bearing 2-sulfoxyl-1,3,4-oxadiazole scaffold for combating COVID-19, EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, ,260
• [6]pengpeiying.A practical preparation of bicyclic boronates via metal-free heteroatom-directed alkenyl sp(2)-C?H borylation, COMMUNICATIONS CHEMISTRY, 2023, ,6(1)
• [7]wangboran.Copper(I)-catalyzed asymmetric 1,3-dipolar cycloaddition of 1,3-enynes and azomethine ylides, NATURE COMMUNICATIONS, 2023, ,14(1)
• [8]wangtao,guanjixun.Cobalt-Catalyzed Chemo- and Stereoselective Arylative Carbocyclization of 1,6-Allenynes, ORGANIC LETTERS, 2023, ,25(32):5935-5940
• [9]wangfeng,刘冬兰.Discovery of natural catechol derivatives as covalent SARS-CoV-2 3CLpro inhibitors, INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2024, ,264
• [10]wangyajie.N-Heterocyclic Carbene-Catalyzed Formal Intramolecular [3+2] Annulations of Cyclohexadienone-Tethered Ynals, ORGANIC LETTERS, 2024, ,26(17):3552-3556
• [11]caoxinyu.Identification of benzo[<i> b</i> ]thiophene-1,1-dioxide derivatives as novel PHGDH covalent inhibitors, BIOORGANIC CHEMISTRY, 2024, ,146
• [12]liuxiliang.Recent progress in asymmetric rearrangement reactions mediated by chiral Brønsted acids, ORGANIC CHEMISTRY FRONTIERS, 2024, ,11(17):4934-4953
• [13]wangyifan.Enantioselective Reductive Cyclization of Alkynyl-Tethered Cyclohexadienones Catalyzed by Rhodium Complexes, ORGANIC LETTERS, 2024,
• [14]wangyifan.Rhodium(III)-catalyzed diastereo- and enantioselective hydrosilylation/cyclization reaction of cyclohexadienone-tethered α, β-unsaturated aldehydes, CHINESE CHEMICAL LETTERS, 2024, ,35(9)
• [15]Synthesis of Polysubstituted Cyclohexenes via Pyridine-Boryl Radical-Catalyzed Formal [4 + 2] Cycloadditions of Cyclobutanes with Alkynes, Hua Huang, Yun-Xuan Tan,* and Ping Tian*,, Org. Lett., 2025, 27, 8123–8128. (IF 5.0),
• [16]Discovery of natural catechol derivatives as covalent SARS-CoV-2 3CLpro inhibitors, Int. J. Biol. Macromol. 2024, 264, 130377. (IF 7.7),
• [17]Nature-Inspired Catalytic Asymmetric Rearrangement of Cyclopropylcarbinyl Cation, Qing-Hua Li,# Gui-Shan Zhang,# Feng Wang, Yixin Cen, Xi-Liang Liu, Jian-Wei Zhang, Yu-Hui Wang,* Albert W. M. Lee,* Dingding Gao,* Guo-Qiang Lin, and Ping Tian*, Sci. Adv. 2023, 9, eadg1237. (IF 13.1),
• [18]Copper(I)-catalyzed asymmetric 1,3-dipolar cycloaddition of 1,3-enynes and azomethine ylides, Bo-Ran Wang, Yan-Bo Li, Qi Zhang, Dingding Gao, Ping Tian,* Qinghua Li,* and Liang Yin*, Nat. Commun. 2023, 14, 4688. (IF 16.6),
• [19]Discovery of Novel Drug-like PHGDH Inhibitors to Disrupt Serine Biosynthesis for Cancer Therapy, Dingding Gao,#* Shuai Tang,# Yixin Cen,# Liang Yuan, Xiaojing Lan, Qing-Hua Li,* Guo-Qiang Lin, Min Huang,* and Ping Tian* J. Med. Chem. 2023, 66, 285−305. (IF 6.8, JCR Q1),

科研项目

• 1、上海市东方英才领军项目,60.0万元, 在研
• 2、国家自然基金面上项目《中心手性到轴手性的传递：手性酸催化的不对称二烯酮-苯酚重排反应构建轴手性化合物》,50.0万元, 在研
• 3、国家重点研发计划课题《药代药效动力学模型驱动的临床干预智能交互生理人关键技术研究》,400.0万元,